FNDC5/Irisin System in Neuroinflammation and Neurodegenerative Diseases: Update and Novel Perspective

Irisin, the circulating peptide originating from fibronectin type III domain-containing protein 5 (FNDC5), is mainly expressed by muscle fibers under peroxisome proliferator-activated receptor gamma coactivator 1-alpha PGC1α control during exercise. In addition to several beneficial effects on healt...

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Bibliographic Details
Main Authors: Patrizia Pignataro, Manuela Dicarlo, Roberta Zerlotin, Chiara Zecca, Maria Teresa Dell’Abate, Cinzia Buccoliero, Giancarlo Logroscino, Silvia Colucci, Maria Grano
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/22/4/1605