Polymorphism in leptin receptor gene was associated with obesity in Yogyakarta, Indonesia

Background: Leptin is a hormone that regulates homeostasis energy through the central–peripheral mechanism as well as regulates hunger and satiety. Leptin receptor is important in leptin signal transduction that is located mainly in the hypothalamus. The mutation in leptin receptor (LEPR) gene cause...

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Bibliographic Details
Main Authors: Pramudji Hastuti, Izza Zukhrufia, Made Harumi Padwaswari, Afifah Nuraini, Ahmad Hamim Sadewa
Format: Article
Language:English
Published: SpringerOpen 2016-07-01
Series:Egyptian Journal of Medical Human Genetics
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1110863015001342