Modeling the Molecular Impact of SARS-CoV-2 Infection on the Renin-Angiotensin System

SARS-CoV-2 infection is mediated by the binding of its spike protein to the angiotensin-converting enzyme 2 (ACE2), which plays a pivotal role in the renin-angiotensin system (RAS). The study of RAS dysregulation due to SARS-CoV-2 infection is fundamentally important for a better understanding of th...

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Bibliographic Details
Main Authors: Fabrizio Pucci, Philippe Bogaerts, Marianne Rooman
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/12/12/1367