Genomic stratification based on microenvironment immune types and PD-L1 for tailoring therapeutic strategies in bladder cancer
Abstract Background The tumour microenvironment (TME) not only plays a role during tumour progression and metastasis but also profoundly influences treatment efficacy. Environment-mediated drug resistance is a result of crosstalk between tumour cells and stroma. The presence of a “stromal exhaustion...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2021-05-01
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Series: | BMC Cancer |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12885-021-08350-1 |