Genomic stratification based on microenvironment immune types and PD-L1 for tailoring therapeutic strategies in bladder cancer

Abstract Background The tumour microenvironment (TME) not only plays a role during tumour progression and metastasis but also profoundly influences treatment efficacy. Environment-mediated drug resistance is a result of crosstalk between tumour cells and stroma. The presence of a “stromal exhaustion...

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Bibliographic Details
Main Authors: Xintong Lyu, Ping Wang, Qiao Qiao, Yuanjun Jiang
Format: Article
Language:English
Published: BMC 2021-05-01
Series:BMC Cancer
Subjects:
Online Access:https://doi.org/10.1186/s12885-021-08350-1