Effects of low-dose ionising radiation on pituitary adenoma: is there a role for L-type calcium channel?

Pituitary adenomas constitute about 6-18% of brain tumours in adults. Activation of voltage gated calcium currents can account for growth hormone oversecretion in some GH-secreting pituitary adenomas that produce an acromegaly appearance and increase mortality. Ca2+ ions, as mediators of intracellul...

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Bibliographic Details
Main Authors: Marcella Araugio Soares, Raquel Gouvêa dos Santos
Format: Article
Language:English
Published: Instituto de Tecnologia do Paraná (Tecpar) 2005-10-01
Series:Brazilian Archives of Biology and Technology
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132005000700028