Upregulation of gelatinases and epithelial-mesenchymal transition in small airway remodeling associated with chronic exposure to wood smoke.

<h4>Background</h4>Peribronchiolar fibrosis is an important feature of small airway remodeling (SAR) in cigarette smoke-induced COPD. The aim of this study was to investigate the role of gelatinases (MMP9, MMP2) and epithelial-mesenchymal transition (EMT) in SAR related to wood smoke (WS...

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Bibliographic Details
Main Authors: Yimin Zou, Shaoxing Li, Weifeng Zou, Guoping Hu, Yumin Zhou, Gongyong Peng, Fang He, Bing Li, Pixin Ran
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24802298/pdf/?tool=EBI