SUMO Wrestles with Recombination

DNA double-strand breaks (DSBs) comprise one of the most toxic DNA lesions, as the failure to repair a single DSB has detrimental consequences on the cell. Homologous recombination (HR) constitutes an error-free repair pathway for the repair of DSBs. On the other hand, when uncontrolled, HR can lead...

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Bibliographic Details
Main Authors: Lumír Krejčí, Peter Kolesár, Veronika Altmannová
Format: Article
Language:English
Published: MDPI AG 2012-07-01
Series:Biomolecules
Subjects:
Online Access:http://www.mdpi.com/2218-273X/2/3/350