A Combined Bi-objective Optimization and Bayesian Framework to Postulate Pharmacometric Compartmental Models

Recently, some applications of Process Systems Engineering to physiology and clinical medicine make use of compartmental analysis to represent transport of material in biological processes. One of the first steps of this analysis is to generate a set of plausible models that describe the system unde...

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Bibliographic Details
Main Authors: José M. Laínez-Aguirre, Luis Puigjaner
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Energy Research
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fenrg.2019.00037/full