Deregulated expression of HDAC9 in B cells promotes development of lymphoproliferative disease and lymphoma in mice
Histone deacetylase 9 (HDAC9) is expressed in B cells, and its overexpression has been observed in B-lymphoproliferative disorders, including B-cell non-Hodgkin lymphoma (B-NHL). We examined HDAC9 protein expression and copy number alterations in primary B-NHL samples, identifying high HDAC9 express...
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
The Company of Biologists
2016-12-01
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Series: | Disease Models & Mechanisms |
Subjects: | |
Online Access: | http://dmm.biologists.org/content/9/12/1483 |