Treatment with Anti-Interleukin 23 Antibody Ameliorates Disease in Lupus-Prone Mice

Treatment with Anti-Interleukin 23 Antibody Ameliorates Disease in Lupus-Prone Mice

Interleukin 23 receptor expressing IL-17 producing T cells have been shown to be important in the development of murine lupus. The usefulness of IL-23 inhibition in ameliorating lupus nephritis is unknown. We hypothesized that inhibition of IL-23 will ameliorate nephritis in lupus-prone mice. To thi...

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Bibliographic Details
Main Authors:	Vasileios C. Kyttaris, Ourania Kampagianni, George C. Tsokos
Format:	Article
Language:	English
Published:	Hindawi Limited 2013-01-01
Series:	BioMed Research International
Online Access:	http://dx.doi.org/10.1155/2013/861028

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