Treatment with Anti-Interleukin 23 Antibody Ameliorates Disease in Lupus-Prone Mice

Interleukin 23 receptor expressing IL-17 producing T cells have been shown to be important in the development of murine lupus. The usefulness of IL-23 inhibition in ameliorating lupus nephritis is unknown. We hypothesized that inhibition of IL-23 will ameliorate nephritis in lupus-prone mice. To thi...

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Bibliographic Details
Main Authors: Vasileios C. Kyttaris, Ourania Kampagianni, George C. Tsokos
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2013/861028