Electrospun PLLA nanofiber scaffolds and their use in combination with BMP-2 for reconstruction of bone defects.

Electrospun PLLA nanofiber scaffolds and their use in combination with BMP-2 for reconstruction of bone defects.

Adequate migration and differentiation of mesenchymal stem cells is essential for regeneration of large bone defects. To achieve this, modern graft materials are becoming increasingly important. Among them, electrospun nanofiber scaffolds are a promising approach, because of their high physical poro...

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Bibliographic Details
Main Authors: Markus D Schofer, Philip P Roessler, Jan Schaefer, Christina Theisen, Sonja Schlimme, Johannes T Heverhagen, Maximilian Voelker, Roland Dersch, Seema Agarwal, Susanne Fuchs-Winkelmann, Jürgen R J Paletta
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3182232?pdf=render

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http://europepmc.org/articles/PMC3182232?pdf=render

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