Mechanisms of lifespan extension and preventive effects of calorie restriction on tumor development: Possible link between central neuroendocrine system and peripheral metabolic adaptation

Mechanisms of lifespan extension and preventive effects of calorie restriction on tumor development: Possible link between central neuroendocrine system and peripheral metabolic adaptation

Restriction of food intake (calorie restriction [CR]) in laboratory animals extends their lifespan and delays the onset of various age-associated diseases, including cancer development. Recent studies revealed that the molecular mechanisms underlying CR-mediated anti-aging effects may be regulated b...

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Bibliographic Details
Main Authors: Takuya Chiba, Kesu Dong, Shoko Nishizono, Isao Shimokawa
Format: Article
Language:English
Published: Japanese Society of Physical Fitness and Sports Medicine 2013-09-01
Series:Journal of Physical Fitness and Sports Medicine
Subjects:
aging
calorie restriction
glucose metabolism
neuroendocrine
oxidative stress
Online Access:https://www.jstage.jst.go.jp/article/jpfsm/2/3/2_259/_pdf/-char/en

Internet

https://www.jstage.jst.go.jp/article/jpfsm/2/3/2_259/_pdf/-char/en

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