TSPO PET upregulation predicts epileptic phenotype at disease onset independently from chronic TSPO expression in a rat model of temporal lobe epilepsy

TSPO PET upregulation predicts epileptic phenotype at disease onset independently from chronic TSPO expression in a rat model of temporal lobe epilepsy

Neuroinflammation is a key component of epileptogenesis, the process leading to acquired epilepsy. In recent years, with the development of non-invasive in vivo positron emission tomography (PET) imaging of translocator protein 18 kDa (TSPO), a marker of neuroinflammation, it has become possible to...

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Bibliographic Details
Main Authors: Daniele Bertoglio, Halima Amhaoul, Joery Goossens, Idrish Ali, Elisabeth Jonckers, Tom Bijnens, Matteo Siano, Leonie wyffels, Jeroen Verhaeghe, Annemie Van der Linden, Steven Staelens, Stefanie Dedeurwaerdere
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:NeuroImage: Clinical
Subjects:
Translocator protein
Inflammation
PET imaging
Neuroimaging
Kainic acid
KASE
Online Access:http://www.sciencedirect.com/science/article/pii/S2213158221001455

Internet

http://www.sciencedirect.com/science/article/pii/S2213158221001455

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