Huaier Extract Inhibits Prostate Cancer Growth via Targeting AR/AR-V7 Pathway

Huaier Extract Inhibits Prostate Cancer Growth via Targeting AR/AR-V7 Pathway

The androgen receptor (AR) plays a pivotal role in prostatic carcinogenesis, and it also affects the transition from hormone sensitive prostate cancer (HSPC) to castration-resistant prostate cancer (CRPC). Particularly, the persistent activation of the androgen receptor and the appearance of androge...

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Bibliographic Details
Main Authors: Zhengfang Liu, Cheng Liu, Keqiang Yan, Jikai Liu, Zhiqing Fang, Yidong Fan
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Oncology
Subjects:
huaier extract
prostate cancer
full length androgen receptor (AR-FL)
androgen receptor splicing variant 7 (AR-V7)
enzalutamide
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.615568/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.615568/full

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