Low Dose Cyclophosphamide Modulates Tumor Microenvironment by TGF-β Signaling Pathway

Low Dose Cyclophosphamide Modulates Tumor Microenvironment by TGF-β Signaling Pathway

The tumor microenvironment has been recently recognized as a critical contributor to cancer progression and anticancer therapy-resistance. Cyclophosphamide (CTX) is a cytotoxic agent commonly used in clinics for the treatment of cancer. Previous reports demonstrated that CTX given at low continuous...

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Bibliographic Details
Main Authors: Hui Zhong, Yifan Lai, Rui Zhang, Abdelkader Daoud, Qingyuan Feng, Jia Zhou, Jing Shang
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:International Journal of Molecular Sciences
Subjects:
cyclophosphamide
tumor microenvironment
metronomic schedule
tgf-β
Online Access:https://www.mdpi.com/1422-0067/21/3/957

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https://www.mdpi.com/1422-0067/21/3/957

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