A combination of quinidine/mexiletine reduces arrhythmia in dilated cardiomyopathy in two patients with R814W SCN5A mutation

A combination of quinidine/mexiletine reduces arrhythmia in dilated cardiomyopathy in two patients with R814W SCN5A mutation

Abstract SCN5A gene mutations are described in 2% of patients with dilated cardiomyopathy (DCM) and different rhythm disturbances, including multifocal ectopic Purkinje‐related premature contractions. Recent data indicate that sodium channel blockers are particularly effective monotherapy in carrier...

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Bibliographic Details
Main Authors: Joanna Zakrzewska‐Koperska, Zofia T. Bilińska, Grażyna T. Truszkowska, Maria Franaszczyk, Waldemar Elikowski, Grzegorz Warmiński, Katarzyna Kalin, Piotr Urbanek, Robert Bodalski, Michał Orczykowski, Łukasz Szumowski, Rafał Płoski, Maria Bilińska
Format: Article
Language:English
Published: Wiley 2020-12-01
Series:ESC Heart Failure
Subjects:
R814W SCN5A variant
Arrhythmogenic dilated cardiomyopathy
Multifocal ectopic Purkinje‐related premature contractions
Online Access:https://doi.org/10.1002/ehf2.12993

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