Protective effect of the organotelluroxetane RF-07 in pilocarpine-induced status epilepticus

Temporal lobe epilepsy is the most common form of epilepsy in humans. Caspase activation is a mechanism of cell death induced by seizures. Tellurium (IV) compounds present antitumoral, immunomodulatory and neuroprotective effects due to their ability to inhibit cysteine proteases. We studied the act...

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Main Authors: Daniele Suzete Persike, Rodrigo Luiz Oliveira Rodrigues Cunha, Luiz Juliano, Iara Ribeiro Silva, Fernanda Elisa Rosim, Thiago Vignoli, Flavia Dona, Esper Abrão Cavalheiro, Maria José da Silva Fernandes
Format: Article
Language:English
Published: Elsevier 2008-07-01
Series:Neurobiology of Disease
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996108000703