Molecular Characteristics and Clinical Outcomes of EGFR Exon 19 C-Helix Deletion in Non–Small Cell Lung Cancer and Response to EGFR TKIs

Molecular Characteristics and Clinical Outcomes of EGFR Exon 19 C-Helix Deletion in Non–Small Cell Lung Cancer and Response to EGFR TKIs

Epidermal growth factor receptor (EGFR) exon 19 deletion (E19del) is the most common activating mutation in advanced non–small cell lung cancer (NSCLC) and associates with the sensitivity of EGFR tyrosine kinase inhibitors (TKIs) treatment. However, not all mutant patterns of E19del have been well s...

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Bibliographic Details
Main Authors: Chun-wei Xu, Lei Lei, Wen-xian Wang, Li Lin, You-cai Zhu, Hong Wang, Li-yun Miao, Li-ping Wang, Wu Zhuang, Mei-yu Fang, Tang-feng Lv, Yong Song
Format: Article
Language:English
Published: Elsevier 2020-09-01
Series:Translational Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523319307211

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http://www.sciencedirect.com/science/article/pii/S1936523319307211

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