DAP3 Is Involved in Modulation of Cellular Radiation Response by RIG-I-Like Receptor Agonist in Human Lung Adenocarcinoma Cells

DAP3 Is Involved in Modulation of Cellular Radiation Response by RIG-I-Like Receptor Agonist in Human Lung Adenocarcinoma Cells

Retinoic acid-inducible gene-I (RIG-I)-like receptors (RLRs) mediate anti-viral response through mitochondria. In addition, RLR activation induces anti-tumor effects on various cancers. We previously reported that the RLR agonist Poly(I:C)-HMW/LyoVec™ (Poly(I:C)) enhanced radiosensitivity and that c...

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Bibliographic Details
Main Authors: Yoshiaki Sato, Hironori Yoshino, Ikuo Kashiwakura, Eichi Tsuruga
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:International Journal of Molecular Sciences
Subjects:
retinoic acid-inducible gene-I-like receptor
ionizing radiation
radiosensitivity
mitochondria
death-associated protein 3
lung adenocarcinoma
Online Access:https://www.mdpi.com/1422-0067/22/1/420

Internet

https://www.mdpi.com/1422-0067/22/1/420

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