SUMOylation Promotes Nuclear Import and Stabilization of Polo-like Kinase 1 to Support Its Mitotic Function
As a pivotal mitotic regulator, polo-like kinase 1 (PLK1) is under highly coordinated and multi-layered regulation. However, the pathways that control PLK1’s activity and function have just begun to be elucidated. PLK1 has recently been shown to be functionally modulated by post-translational modifi...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2017-11-01
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Series: | Cell Reports |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124717315486 |