Human ES Cell Culture Conditions Fail to Preserve the Mouse Epiblast State

Mouse embryonic stem cells (mESCs) and mouse epiblast stem cells (mEpiSCs) are the pluripotent stem cells (PSCs), derived from the inner cell mass (ICM) of preimplantation embryos at embryonic day 3.5 (E3.5) and postimplantation embryos at E5.5-E7.5, respectively. Depending on their environment, PSC...

Full description

Bibliographic Details
Main Authors: A. S. Devika, Anna Montebaur, S. Saravanan, Raghu Bhushan, Frederic Koch, Smita Sudheer
Format: Article
Language:English
Published: Hindawi Limited 2021-01-01
Series:Stem Cells International
Online Access:http://dx.doi.org/10.1155/2021/8818356