Therapeutic Effects of Berberine Hydrochloride on Stress-Induced Diarrhea-Predominant Irritable Bowel Syndrome Rats by Inhibiting Neurotransmission in Colonic Smooth Muscle

Therapeutic Effects of Berberine Hydrochloride on Stress-Induced Diarrhea-Predominant Irritable Bowel Syndrome Rats by Inhibiting Neurotransmission in Colonic Smooth Muscle

The etiology of diarrhea-predominant irritable bowel syndrome (IBS-D) is complicated and closely related to neurotransmission in the gastrointestinal (GI) tract. Developing new strategies for treating this disease is a major challenge for IBS-D research. Berberine hydrochloride (BBH), the derivative...

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Bibliographic Details
Main Authors: Yulin Lu, Jingjing Huang, Yao Zhang, Zitong Huang, Weiming Yan, Tianran Zhou, Zhesheng Wang, Lu Liao, Hongying Cao, Bo Tan
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Pharmacology
Subjects:
berberine hydrochloride
diarrhea-predominant irritable bowel syndrome
colonic longitudinal smooth muscles
inhibitory effects
neurotransmission
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.596686/full

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https://www.frontiersin.org/articles/10.3389/fphar.2021.596686/full

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