Diospyrin Modulates Inflammation in Poly I:C-Induced Macrophages via ER Stress-Induced Calcium-CHOP Pathway

Diospyrin, plant-derived bisnaphthoquinonoid, is known to have anticancer activity. However, pharmacological activity of diospyrin on viral infection is not well known. We investigated effects of diospyrin on macrophages induced by polyinosinic-polycytidylic acid (poly I:C), a mimic of double-strand...

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Bibliographic Details
Main Authors: Hyun-Ju Kim, Inamullah Khan, Adnan Shahidullah, Syed Muhammad Ashhad Halimi, Abdur Rauf, Ji-Young Lee, Young-Jin Kim, Bong-Youn Kim, Wansu Park
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Processes
Subjects:
Online Access:https://www.mdpi.com/2227-9717/8/9/1050