Increased Expression of the Pro-Protein Convertase Furin Predicts Decreased Survival in Ovarian Cancer

Background: Proprotein convertases (PCs) are serine proteases that after restricted proteolysis activate many proteins that play a crucial role in cancer such as metalloproteinases, growth factors and growth factor receptors, adhesion molecules, and angiogenic factors. Although the expression of sev...

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Bibliographic Details
Main Authors: Robert E. Page, Andrés J. P. Klein-Szanto, Samuel Litwin, Emmanuelle Nicolas, Raid Al-Jumaily, Peter Alexander, Andrew K. Godwin, Eric A. Ross, Russell J. Schilder, Daniel E. Bassi
Format: Article
Language:English
Published: Hindawi Limited 2007-01-01
Series:Cellular Oncology
Online Access:http://dx.doi.org/10.1155/2007/930321