Increased Expression of the Pro-Protein Convertase Furin Predicts Decreased Survival in Ovarian Cancer
Background: Proprotein convertases (PCs) are serine proteases that after restricted proteolysis activate many proteins that play a crucial role in cancer such as metalloproteinases, growth factors and growth factor receptors, adhesion molecules, and angiogenic factors. Although the expression of sev...
Main Authors: | , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2007-01-01
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Series: | Cellular Oncology |
Online Access: | http://dx.doi.org/10.1155/2007/930321 |