Nanolipoparticles-mediated MDR1 siRNA delivery: preparation, characterization and cellular uptake
Objective(s): Lipid-based nanoparticles (NLP) are PEGylated carriers composed of lipids and encapsulated nucleic acids with a diameter less than 100 nm. The presence of PEG in the NLP formulation improves the particle pharmacokinetic behavior. The purpose of this study was to prepare and characteriz...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Mashhad University of Medical Sciences
2015-01-01
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Series: | Nanomedicine Journal |
Subjects: | |
Online Access: | http://nmj.mums.ac.ir/pdf_3467_c5d9c11f9ed269c7e3041f316fa5bb82.html |