Helical-Track Bioreactors for Bacterial, Mammalian and Insect Cell Cultures

Helical-Track Bioreactors for Bacterial, Mammalian and Insect Cell Cultures

We investigated the cultivation of bacterial, mammalian and insect cells in an orbitally-shaken 250-mL disposable tube that incorporates a helical track (HT) on its inside wall. The mass transfer coefficient of oxygen (kLa) was 200%–400% higher in the HT tube than in a shake flask. Bacterial growth a...

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Bibliographic Details
Main Authors: Stéphanie Tissot, Patrik O. Michel, Clara J. Douet, Sarah Grezet, Lucia Baldi, David L. Hacker, Florian M. Wurm
Format: Article
Language:English
Published: MDPI AG 2013-03-01
Series:Processes
Subjects:
shake flasks
orbital shaking
bacteria
gas transfer
insect cells
mammalian cells
Online Access:http://www.mdpi.com/2227-9717/1/1/3

Internet

http://www.mdpi.com/2227-9717/1/1/3

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