Label-free classification of cells based on supervised machine learning of subcellular structures.

It is demonstrated that cells can be classified by pattern recognition of the subcellular structure of non-stained live cells, and the pattern recognition was performed by machine learning. Human white blood cells and five types of cancer cell lines were imaged by quantitative phase microscopy, whic...

Full description

Bibliographic Details
Main Authors: Yusuke Ozaki, Hidenao Yamada, Hirotoshi Kikuchi, Amane Hirotsu, Tomohiro Murakami, Tomohiro Matsumoto, Toshiki Kawabata, Yoshihiro Hiramatsu, Kinji Kamiya, Toyohiko Yamauchi, Kentaro Goto, Yukio Ueda, Shigetoshi Okazaki, Masatoshi Kitagawa, Hiroya Takeuchi, Hiroyuki Konno
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0211347