Depleting SOX2 improves ischemic stroke via lncRNA PVT1/microRNA-24-3p/STAT3 axis

Depleting SOX2 improves ischemic stroke via lncRNA PVT1/microRNA-24-3p/STAT3 axis

Abstract Objectives Studies have widely explored in the filed of ischemic stroke (IS) with their focus on transcription factors. However, few studies have pivoted on sex determining region Y-box 2 (SOX2) in IS. Thus, this study is launched to figure out the mechanisms of SOX2 in IS. Methods Rat midd...

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Bibliographic Details
Main Authors: Zhongjun Chen, Tieping Fan, Xusheng Zhao, Zhichen Zhang
Format: Article
Language:English
Published: BMC 2021-09-01
Series:Molecular Medicine
Subjects:
Ischemic stroke
Sex determining region Y-box 2
Signal transducer and activator of transcription 3
Long non-coding RNA plasmacytoma variant translocation 1
MicroRNA-24-3p
Oxidative stress
Online Access:https://doi.org/10.1186/s10020-021-00346-8

Internet

https://doi.org/10.1186/s10020-021-00346-8

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