A neoepitope derived from a novel germline Adenomatous polyposis coli (APC) gene mutation in Familial Adenomatous Polyposis (FAP) shows selective immunogenicity

A neoepitope derived from a novel germline Adenomatous polyposis coli (APC) gene mutation in Familial Adenomatous Polyposis (FAP) shows selective immunogenicity

Familial Adenomatous Polyposis (FAP) is characterized by the manifestation of adenomatous polyps in the colon and rectum at an early age (mean age of 16), which if left untreated, leads to aggressive and fatal tumors by the age of 40 years. FAP is caused by autosomal dominant inheritance of germ lin...

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Bibliographic Details
Main Authors: Snigdha Majumder, Rakshit Shah, Jisha Elias, Yogesh Mistry, Coral Karunakaran, Priyanka Shah, Anand Kumar Maurya, Bharti Mittal, Jason K. D'Silva, Lakshmi Mahadevan, Rekha Sathian, Ravi Gupta, Amitabha Chaudhuri, Arati Khanna- Gupta
Format: Article
Language:English
Published: Science Planet Inc. 2017-12-01
Series:Canadian Journal of Biotechnology
Online Access:https://www.canadianjbiotech.com/CAN_J_BIOTECH/Archives/v1/Special Issue-Supplement/cjb.2017-a236.pdf

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https://www.canadianjbiotech.com/CAN_J_BIOTECH/Archives/v1/Special Issue-Supplement/cjb.2017-a236.pdf

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