Amyloid β Oligomeric Species Present in the Lag Phase of Amyloid Formation.

Alzheimer's disease (AD)-associated amyloid β peptide (Aβ) is one of the main actors in AD pathogenesis. Aβ is characterized by its high tendency to self-associate, leading to the generation of oligomers and amyloid fibrils. The elucidation of pathways and intermediates is crucial for the under...

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Bibliographic Details
Main Authors: Martin Wolff, Dmitry Unuchek, Bo Zhang, Valentin Gordeliy, Dieter Willbold, Luitgard Nagel-Steger
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4449029?pdf=render