Electroacupuncture Attenuates Visceral Hypersensitivity by Inhibiting JAK2/STAT3 Signaling Pathway in the Descending Pain Modulation System

Electroacupuncture Attenuates Visceral Hypersensitivity by Inhibiting JAK2/STAT3 Signaling Pathway in the Descending Pain Modulation System

Electroacupuncture (EA) has been used for treating visceral hypersensitivity (VH). However, the underlying molecular mechanism remains unclear. This study was aim to testify the effect of EA on ileitis-provoked VH, and to confirm whether EA attenuates VH through Janus kinase 2 (JAK2)/signal transduc...

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Bibliographic Details
Main Authors: Juan Wan, Yi Ding, Adnan H. Tahir, Manoj K. Shah, Habibullah Janyaro, Xiaojing Li, Juming Zhong, Vitaly Vodyanoy, Mingxing Ding
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-11-01
Series:Frontiers in Neuroscience
Subjects:
electroacupuncture (EA)
TNBS
visceral hypersensitivity (VH)
visceromotor response (VMR)
JAK2/STAT3 signaling pathway
PAG-RVM-SCDH axis
Online Access:http://journal.frontiersin.org/article/10.3389/fnins.2017.00644/full

Internet

http://journal.frontiersin.org/article/10.3389/fnins.2017.00644/full

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