Sequential allocation to balance prognostic factors in a psychiatric clinical trial
OBJECTIVE: This paper aims to describe and discuss a minimization procedure specifically designed for a clinical trial that evaluates treatment efficacy for OCD patients. METHOD: Aitchison's compositional distance was used to calculate vectors for each possibility of allocation in a covariate a...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Faculdade de Medicina / USP
2009-06-01
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Series: | Clinics |
Subjects: | |
Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322009000600005 |