miR-122 Targets X-Linked Inhibitor of Apoptosis Protein to Sensitize Oxaliplatin-Resistant Colorectal Cancer Cells to Oxaliplatin-Mediated Cytotoxicity

miR-122 Targets X-Linked Inhibitor of Apoptosis Protein to Sensitize Oxaliplatin-Resistant Colorectal Cancer Cells to Oxaliplatin-Mediated Cytotoxicity

Background/Aims: Although oxaliplatin is one of the most effective chemotherapeutic drugs used to treat colorectal cancer (CRC), long-term administration usually induces acquired drug resistance during the course of treatment. Thus, there is an urgent need to explore novel strategies to improve the...

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Bibliographic Details
Main Authors: Yongqiang Hua, Yaodong Zhu, Jijie Zhang, Zhenfeng Zhu, Zhouyu Ning, Hao Chen, Luming Liu, Zhen Chen, Zhiqiang  Meng
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-12-01
Series:Cellular Physiology and Biochemistry
Subjects:
miR-122
XIAP
Colorectal cancer
Oxaliplatin resistance
Online Access:https://www.karger.com/Article/FullText/495832

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https://www.karger.com/Article/FullText/495832

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