RNA-Dependent RNA Polymerases of Picornaviruses: From the Structure to Regulatory Mechanisms

RNA viruses typically encode their own RNA-dependent RNA polymerase (RdRP) to ensure genome replication within the infected cells. RdRP function is critical not only for the virus life cycle but also for its adaptive potential. The combination of low fidelity of replication and the absence of proofr...

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Bibliographic Details
Main Authors: Cristina Ferrer-Orta, Diego Ferrero, Núria Verdaguer
Format: Article
Language:English
Published: MDPI AG 2015-08-01
Series:Viruses
Subjects:
Online Access:http://www.mdpi.com/1999-4915/7/8/2829