Evaluation of an Intrathecal Immune Response in Amyotrophic Lateral Sclerosis Patients Implanted with Encapsulated Genetically Engineered Xenogeneic Cells

A phase I/II clinical trial has been performed in 12 amyotrophic lateral sclerosis (ALS) patients to evaluate the safety and tolerability of intrathecal implants of encapsulated genetically engineered baby hamster kidney (BHK) cells releasing human ciliary neurotrophic factor (CNTF). These patients...

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Bibliographic Details
Main Authors: A. D. Zurn, H. Henry, M. Schluep, V. Aubert, L. Winkel, B. Eilers, C. Bachmann, P. Aebischer
Format: Article
Language:English
Published: SAGE Publishing 2000-07-01
Series:Cell Transplantation
Online Access:https://doi.org/10.1177/096368970000900404