Doublecortin knockout mice show normal hippocampal-dependent memory despite CA3 lamination defects.

Doublecortin knockout mice show normal hippocampal-dependent memory despite CA3 lamination defects.

Mutations in the human X-linked doublecortin gene (DCX) cause major neocortical disorganization associated with severe intellectual disability and intractable epilepsy. Although Dcx knockout (KO) mice exhibit normal isocortical development and architecture, they show lamination defects of the hippoc...

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Bibliographic Details
Main Authors: Johanne Germain, Elodie Bruel-Jungerman, Gael Grannec, Cécile Denis, Gabriel Lepousez, Bruno Giros, Fiona Francis, Marika Nosten-Bertrand
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3779246?pdf=render

Internet

http://europepmc.org/articles/PMC3779246?pdf=render

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