Accurate, model-based tuning of synthetic gene expression using introns in S. cerevisiae.
Introns are key regulators of eukaryotic gene expression and present a potentially powerful tool for the design of synthetic eukaryotic gene expression systems. However, intronic control over gene expression is governed by a multitude of complex, incompletely understood, regulatory mechanisms. Despi...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-06-01
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Series: | PLoS Genetics |
Online Access: | http://europepmc.org/articles/PMC4072511?pdf=render |