Germacrone alleviates neurological deficits following traumatic brain injury by modulating neuroinflammation and oxidative stress

Germacrone alleviates neurological deficits following traumatic brain injury by modulating neuroinflammation and oxidative stress

Abstract Background Germacrone (GM) is a terpenoid compound which is reported to have anti-inflammatory and anti-oxidative effects. However, its role in treating traumatic brain injury (TBI) remains largely unknown. Methods Male C57BL/6 mice were divided into the following groups: control group, TBI...

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Bibliographic Details
Main Authors: Sujing Zhuang, Baogui Liu, Shifeng Guo, Yanzhong Xue, Lin Wu, Shiqi Liu, Chunling Zhang, Xiuyan Ni
Format: Article
Language:English
Published: BMC 2021-01-01
Series:BMC Complementary Medicine and Therapies
Subjects:
Germacrone
Traumatic brain injury
NF-κB
Inflammation
Online Access:https://doi.org/10.1186/s12906-020-03175-0

Internet

https://doi.org/10.1186/s12906-020-03175-0

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