Hsp90 chaperone facilitates E2F1/2-dependent gene transcription in human breast cancer cells
The 90 kDa heat shock protein, Hsp90, is involved in the conformational stabilization and functional maturation of diverse cancer-promoting proteins. To date, more than 300 Hsp90 clients have identified, suggesting that Hsp90 plays a central role in deciding cancer cell fate. In this study, we prese...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2021-01-01
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Series: | European Journal of Cell Biology |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S017193352030087X |