Hsp90 chaperone facilitates E2F1/2-dependent gene transcription in human breast cancer cells

The 90 kDa heat shock protein, Hsp90, is involved in the conformational stabilization and functional maturation of diverse cancer-promoting proteins. To date, more than 300 Hsp90 clients have identified, suggesting that Hsp90 plays a central role in deciding cancer cell fate. In this study, we prese...

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Bibliographic Details
Main Authors: Akhil Kotwal, Sourabh Suran, Sreedhar Amere Subbarao
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:European Journal of Cell Biology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S017193352030087X