IRGM variants and susceptibility to inflammatory bowel disease in the German population.

IRGM variants and susceptibility to inflammatory bowel disease in the German population.

Genome-wide association studies identified the autophagy gene IRGM to be strongly associated with Crohn's disease (CD) but its impact in ulcerative colitis (UC), its phenotypic effects and potential epistatic interactions with other IBD susceptibility genes are less clear which we therefore ana...

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Bibliographic Details
Main Authors: Jürgen Glas, Julia Seiderer, Stephanie Bues, Johannes Stallhofer, Christoph Fries, Torsten Olszak, Eleni Tsekeri, Martin Wetzke, Florian Beigel, Christian Steib, Matthias Friedrich, Burkhard Göke, Julia Diegelmann, Darina Czamara, Stephan Brand
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3554777?pdf=render

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http://europepmc.org/articles/PMC3554777?pdf=render

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