A Comprehensive Monitoring Study on Electrocardiographic Assessments and Cardiac Events After Fingolimod First Dose—Possible Predictors of Cardiac Outcomes

A Comprehensive Monitoring Study on Electrocardiographic Assessments and Cardiac Events After Fingolimod First Dose—Possible Predictors of Cardiac Outcomes

Background: First dose observation for cardiac effects is required for fingolimod. Previous results in patients with relapsing remitting multiple sclerosis (RRMS) suggest that transient bradycardia and conduction abnormalities during the observation phase are rare, benign and reversible. Prior analy...

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Bibliographic Details
Main Authors: Volker Limmroth, Tjalf Ziemssen, Ingo Kleiter, Bert Wagner, Stephan Schmidt, Christoph Lassek, Monika Baier-Ebert, Guillaume Wendt, Ralf Dechend, Wilhelm Haverkamp
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Neurology
Subjects:
fingolimod
first dose
electrocardiogram
cardiac effects
bradycardia
atrioventricular conduction
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2020.00818/full

Internet

https://www.frontiersin.org/article/10.3389/fneur.2020.00818/full

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