Recombinant Antigen of Type 2 Porcine Reproductive and Respiratory Syndrome Virus (PRRSV-2) Promotes M1 Repolarization of Porcine Alveolar Macrophages and Th1 Type Response

Recombinant Antigen of Type 2 Porcine Reproductive and Respiratory Syndrome Virus (PRRSV-2) Promotes M1 Repolarization of Porcine Alveolar Macrophages and Th1 Type Response

The polarization status of porcine alveolar macrophages (PAMs) determines the infectivity of porcine reproductive and respiratory syndrome virus (PRRSV). PRRSV infection skews macrophage polarization toward an M2 phenotype, followed by T-cells inactivation. CD163, one of the scavenger receptors of M...

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Bibliographic Details
Main Authors: Rika Wahyuningtyas, Yin-Siew Lai, Mei-Li Wu, Hsin-Wei Chen, Wen-Bin Chung, Hso-Chi Chaung, Ko-Tung Chang
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Vaccines
Subjects:
PAMs
CD163
PRRSV
M1
M2
Th1
Online Access:https://www.mdpi.com/2076-393X/9/9/1009

Internet

https://www.mdpi.com/2076-393X/9/9/1009

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