Engineering foot-and-mouth disease viruses with improved growth properties for vaccine development.

Engineering foot-and-mouth disease viruses with improved growth properties for vaccine development.

BACKGROUND: No licensed vaccine is currently available against serotype A foot-and-mouth disease (FMD) in China, despite the isolation of A/WH/CHA/09 in 2009, partly because this strain does not replicate well in baby hamster kidney (BHK) cells. METHODOLOGY/PRINCIPAL FINDINGS: A novel plasmid-based...

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Bibliographic Details
Main Authors: Haixue Zheng, Jianhong Guo, Ye Jin, Fan Yang, Jijun He, Lv Lv, Kesan Zhang, Qiong Wu, Xiangtao Liu, Xuepeng Cai
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3555929?pdf=render

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http://europepmc.org/articles/PMC3555929?pdf=render

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