Significant difference between sirolimus and paclitaxel nanoparticles in anti-proliferation effect in normoxia and hypoxia: The basis of better selection of atherosclerosis treatment

Compared with paclitaxel, sirolimus has been more used in the treatment of vascular restenosis gradually as an anti-proliferative drug, but few basic studies have elucidated its mechanism. The anti-proliferative effects of sirolimus or paclitaxel have been demonstrated by numerous studies under norm...

Full description

Bibliographic Details
Main Authors: Youlu Chen, Yong Zeng, Xiaowei Zhu, Lifu Miao, Xiaoyu Liang, Jianwei Duan, Huiyang Li, Xinxin Tian, Liyun Pang, Yongxiang Wei, Jing Yang
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2021-03-01
Series:Bioactive Materials
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X20302139