IP3 3-kinase opposes NGF driven neurite outgrowth.

The inositol (1,4,5) trisphosphate 3-kinases comprise a family of enzymes (A, B, and C) that phosphorylate the calcium mobilising molecule inositol (1,4,5) trisphosphate (IP(3)) to generate inositol (1,3,4,5) tetrakisphosphate. This molecule can function as a second messenger, but its roles are not...

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Bibliographic Details
Main Authors: Richard Eva, Dalila Bouyoucef-Cherchalli, Kalpana Patel, Peter J Cullen, George Banting
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3284567?pdf=render