Hypoxic pre-conditioning suppresses experimental autoimmune encephalomyelitis by modifying multiple properties of blood vessels

Hypoxic pre-conditioning suppresses experimental autoimmune encephalomyelitis by modifying multiple properties of blood vessels

Abstract While hypoxic pre-conditioning protects against neurological disease the underlying mechanisms have yet to be fully defined. As chronic mild hypoxia (CMH, 10% O2) triggers profound vascular remodeling in the central nervous system (CNS), the goal of this study was to examine the protective...

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Bibliographic Details
Main Authors: Sebok K. Halder, Ravi Kant, Richard Milner
Format: Article
Language:English
Published: BMC 2018-09-01
Series:Acta Neuropathologica Communications
Subjects:
Endothelial
Laminin
Hypoxic pre-conditioning
Experimental autoimmune encephalomyelitis
Blood-brain barrier
Online Access:http://link.springer.com/article/10.1186/s40478-018-0590-5

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http://link.springer.com/article/10.1186/s40478-018-0590-5

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