Evidence of influence of genomic DNA sequence on human X chromosome inactivation.

A significant number of human X-linked genes escape X chromosome inactivation and are thus expressed from both the active and inactive X chromosomes. The basis for escape from inactivation and the potential role of the X chromosome primary DNA sequence in determining a gene's X inactivation sta...

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Bibliographic Details
Main Authors: Zhong Wang, Huntington F Willard, Sayan Mukherjee, Terrence S Furey
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2006-09-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC1557588?pdf=render