Distinct populations of cortical pyramidal neurons mediate drug reward and aversion

The anterior cingulate plays a role in addiction, but studies have not examined the role of its two types of glutamatergic projection neurons, pyramidal tract (PT) and intratelencephalic (IT). Here we demonstrate that these two populations regulate distinct features of a drug experience, its positiv...

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Bibliographic Details
Main Authors: A. F. Garcia, E. A. Crummy, I. G. Webb, M. N. Nooney, S. M. Ferguson
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-20526-0