Novel mutations of PKD genes in Chinese patients suffering from autosomal dominant polycystic kidney disease and seeking assisted reproduction

Novel mutations of PKD genes in Chinese patients suffering from autosomal dominant polycystic kidney disease and seeking assisted reproduction

Abstract Background Autosomal dominant polycystic kidney disease (ADPKD), the commonest inherited kidney disease, is generally caused by heterozygous mutations in PKD1, PKD2, or GANAB (PKD3). Methods We performed mutational analyses of PKD genes to identify causative mutations. A set of 90 unrelated...

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Bibliographic Details
Main Authors: Wen-Bin He, Wen-Juan Xiao, Yue-Qiu Tan, Xiao-Meng Zhao, Wen Li, Qian-Jun Zhang, Chang-Gao Zhong, Xiu-Rong Li, Liang Hu, Guang-Xiu Lu, Ge Lin, Juan Du
Format: Article
Language:English
Published: BMC 2018-10-01
Series:BMC Medical Genetics
Subjects:
Autosomal dominant polycystic kidney disease
PKD1 gene
PKD2 gene
GANAB gene
Novel mutation
Male infertility
Online Access:http://link.springer.com/article/10.1186/s12881-018-0693-7

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http://link.springer.com/article/10.1186/s12881-018-0693-7

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